Site Specific Preparation of N-Glycosylated Peptides: Thioamide-Directed Activation of Aspartate

A new direction in peptide synthesis: an N-to-C approach using thioamides

The synthesis of amide bonds is one of the most important techniques in organic chemistry. Amide bonds are formed in the production of 65% o..

New synthetic strategies to small cyclic peptides

This project aims to invent new synthetic strategies that enable chemical manipulation of small cyclic peptides, a promising class of biolog..

Thioamide ligations: new technologies for peptide and protein synthesis

This project aims to develop novel amide-bond forming reactions for the chemical synthesis of peptides and proteins. New peptide ligation st..